Long term surgical outcome for persistent pupillary membranes with associated ocular abnormalities: a retrospective case series study

Abstract Background Deprivation amblyopia is a great concern in hyperplastic persistent pupillary membranes (PPM) which blocked visual axis. Other ocular abnormality may accompany and further hinder the development of infants. We evaluate long-term prognosis complications patients with dense PPM other associated abnormalities treated early surgical intervention timely rehabilitation. Methods Medical records removal from 2000 to 2020 also receiving rehabilitation were retrospectively reviewed. Besides axis PPM, combined amblyopic risk factors or included. Due preparation for subsequent lens extraction if an underlying cataract was present, settings including instruments wound direction similar surgery. All enrolled program as soon possible. The results sex, age, timing operation, initial final acuity, refractive errors, recorded. Results Seven cases five included this case series. Mean age at surgery 42.3 ± 21.1 months (range, 5 66 months) post-operative follow-up period 4.9 years 1.2 8.2 years). patient time ranged 2.5 (mean, 14 months). postoperative 5.3 2.5–8 There no intra-operative complications. Final BCVA varied mean value 0.29 logMAR 0 1 logMAR). An ametropia strabismus led best prognosis. Conclusions In there significant any using our technique. are easier handle more familiar pediatric surgeons. deprivation patching, achieve ametropic strabismic amblyopia. Trial registration This retrospective, interventional series study conducted China University Hospital between April 1, 31, 2020. (IRB number: CMUH109-REC2–069 ).